Histomorphometric comparison after fixation with formaldehyde or glyoxal

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Formaldehyde fixation.

The use of formaldehyde as a biological reagent occurred rather late in the history of histological methodology. The reason for this lay not in any lack of astuteness on the part of pathologists and histologists, but rather with the late development of formaldehyde manufacture by the chemical industry. While formaldehyde was discovered by Butlerov in 1859, practical aspects of the manufacture o...

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Melamine–Glyoxal–Glutaraldehyde Wood Panel Adhesives without Formaldehyde

Abstract: (MGG’) resin adhesives for bonding wood panels were prepared by a single step procedure, namely reacting melamine with glyoxal and simultaneously with a much smaller proportion of glutaraldehyde. No formaldehyde was used. The inherent slow hardening of this resin was overcome by the addition of N-methyl-2-pyrrolidone hydrogen sulphate ionic liquid as the adhesive hardener in the glue ...

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Glyoxal as an alternative fixative to formaldehyde in immunostaining and super‐resolution microscopy

Paraformaldehyde (PFA) is the most commonly used fixative for immunostaining of cells, but has been associated with various problems, ranging from loss of antigenicity to changes in morphology during fixation. We show here that the small dialdehyde glyoxal can successfully replace PFA Despite being less toxic than PFA, and, as most aldehydes, likely usable as a fixative, glyoxal has not yet bee...

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ژورنال

عنوان ژورنال: Biotechnic & Histochemistry

سال: 2010

ISSN: 1052-0295,1473-7760

DOI: 10.3109/10520295.2010.520275